Journal
TETRAHEDRON-ASYMMETRY
Volume 22, Issue 16-17, Pages 1605-1609Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2011.09.006
Keywords
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Funding
- Japan Society for the Promotion of Science [22590007]
- Grants-in-Aid for Scientific Research [22590007] Funding Source: KAKEN
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Primary amine thiourea organocatalyst 8 was used to promote Michael additions of bulky alpha,alpha-disubstituted aldehydes, such as isobutyraldehyde with maleimides to afford the corresponding adducts in high to excellent yields and with up to 91% ee. (C) 2011 Elsevier Ltd. All rights reserved.
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