4.0 Article

Chiron approach to the synthesis of yashabushidiol B, (3S,5S)-1-(4′-hydroxyphenyl)-7-phenylheptane-3,5-diol, and its 4′-methoxy analogue

Journal

TETRAHEDRON-ASYMMETRY
Volume 22, Issue 1, Pages 8-11

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2010.12.015

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Funding

  1. University of Pune, Pune [BCUD/OSD/184-2009]
  2. UGC (New Delhi, INDIA)

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The total synthesis of yashabushidiol B 4, a linear diarylheptanoid containing a 1,3-diol system and its analogues 5 and 6 has been achieved by utilizing intermediate 7, which was derived from D-glucose. The Wittig reaction is the key step of our synthetic strategy. (C) 2010 Elsevier Ltd. All rights reserved.

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