Journal
TETRAHEDRON-ASYMMETRY
Volume 19, Issue 1, Pages 93-96Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2007.11.039
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A highly enantioselective one pot, novel biocatalytic method for the asymmetric reduction of aryl imines is reported. Treatment of aryl imines with Candida parapsilosis ATCC 7330 in aqueous medium produces the enantiomerically pure (R)-secondary amines in moderate to good yields (55-80%) with excellent enantiomeric excesses (95->99%). (c) 2007 Elsevier Ltd. All rights reserved.
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