4.0 Article

Enantioselective benzoylation of racemic amines using chiral benzimidazolide as a benzoylating agent

Journal

TETRAHEDRON-ASYMMETRY
Volume 19, Issue 1, Pages 45-48

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2007.12.006

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Enantioselective acylation/kinetic resolution of racemic amines has been achieved by using a chiral benzimidazolide, namely, (S)-1-benzoyl-2-(alpha-acetoxyethyl)benzimidazole 2. This nonenzymatic acylating reagent requires mild reaction conditions and proceeds with good enantioselectivity. (c) 2007 Elsevier Ltd. All rights reserved.

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