Journal
TETRAHEDRON LETTERS
Volume 59, Issue 41, Pages 3713-3718Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2018.09.010
Keywords
Solid phase peptide synthesis; Laxaphycin; Trichormamide; Lipocyclopeptide; Cyanobacteria
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Funding
- French Infrastructure for Integrated Structural Biology (FRISBI) [ANR-10-INBS-05]
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Lipocyclopeptides isolated from marine sources hold great promise as new lead for therapeutics. Here, we propose the first attempt towards the total synthesis of Trichormamide A. This synthesis will help to confirm the proposed structure of the cyclic lipopeptide. (C) 2018 Elsevier Ltd. All rights reserved.
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