Journal
TETRAHEDRON LETTERS
Volume 59, Issue 43, Pages 3858-3862Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2018.09.028
Keywords
Fe+3 ion sensors; Live cell imaging; Naphthalene dianhydride based fluorescent probe; PET operating probe
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Funding
- Council of Scientific and Industrial Research (CSIR), Government of India [09/895(0006)/2014-EMR-1]
- MHRD, Govt. of India
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A green emissive PET operating fluorescent turn-on cell permeable novel probe R1 has been successfully developed and utilized for the detection of Fe+3 in the pure aqueous system at sub-nanomolar level. Moreover, probe R1 demonstrate highly sensitive and selective towards Fe+3 over the other divalent and trivalent metal ions and was established by using fluorescence spectroscopy. The efficiency and aid of R1 was demonstrated by the fluorescence imaging of captured Fe+3 within Pollen grains by using fluorescence microscopy, These results indicate that, this is the first fluorescent turn-on PET probe to detect sub-nanomolar Fe+3 in the pure aqueous system and in cellular level. (C) 2018 Elsevier Ltd. All rights reserved.
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