4.4 Article

A mild and efficient copper-catalyzed N-arylation of unprotected sulfonimidamides using boronic acids

Journal

TETRAHEDRON LETTERS
Volume 55, Issue 2, Pages 517-520

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.11.084

Keywords

Sulfonimidamides; Chan-Lam coupling; Boronic acids; Copper-catalyzed coupling; N-arylation

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An efficient and low cost copper catalyzed system for N-arylation of sulfonimidamides has been developed. The reaction proceeds at room temperature under base free conditions. Various N-aryl, N-heteroaryl, and N-cyclopropyl sulfonimidamides were obtained in good to excellent yields. (C) 2013 Elsevier Ltd. All rights reserved.

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