4.4 Article

Chemoenzymatic total synthesis of paecilocin A and 3-butyl-7-hydroxyphthalide

Journal

TETRAHEDRON LETTERS
Volume 55, Issue 7, Pages 1303-1305

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.12.089

Keywords

Paecilocin A; 3-Butyl-7-hydroxyphthalide; Enzymatic kinetic resolution; Alder-Rickert reaction

Funding

  1. CSIR, New Delhi [CSC-0108]

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A highly enantioselective total synthesis of paecilocin A and 3-butyl-7-hydroxyphthalide is described. The key steps involved in this synthesis are enzymatic kinetic resolution and Alder-Rickert reaction. (C) 2014 Elsevier Ltd. All rights reserved.

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