Journal
TETRAHEDRON LETTERS
Volume 55, Issue 19, Pages 3064-3069Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.03.134
Keywords
Microwave-assisted; 1,3-Dipolar cycloaddition; Azomethine imine; Pyrazolopyrroloindole; Stereoselective
Categories
Funding
- Council of Scientific and Industrial Research (CSIR), New Delhi, India
- UGC, New Delhi, India
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The synthesis of [a]-annelated pyrazolopyrroloindoles via intramolecular 1,3-dipolar cycloaddition of in situ generated azomethine imine from N-allylated indole-2-carboxaldehyde, in regio- and stereoselective manner by using microwave irradiation is described. A one-pot strategy for the expedient synthesis of pyrazolopyrroloindoles has been developed. (C) 2014 Elsevier Ltd. All rights reserved.
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