Journal
TETRAHEDRON LETTERS
Volume 55, Issue 14, Pages 2246-2248Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.02.077
Keywords
Diels-Alder cycloaddition; 9-Substituted anthracenes; N-maleimides; Thin film microfluidics; Vortex fluidics
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Funding
- Australian Research Council
- Centre for Microscopy, Characterisation and Analysis at the University of Western Australia
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'Soft energy' provided within a thin film microfluidic platform, namely a vortex fluidic device (VFD), is effective in accelerating and promoting Diels-Alder reactions in the absence of any catalyst. Diels-Alder cycloadducts generated from different 9-substituted anthracenes and N-maleimides are formed in high yield in an aqueous medium using the confined mode of operation of the VFD. (C) 2014 Elsevier Ltd. All rights reserved.
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