4.4 Article

A facile synthesis of novel tricyclic 4-pyridones

Journal

TETRAHEDRON LETTERS
Volume 55, Issue 52, Pages 7194-7197

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.11.003

Keywords

4-Pyridone; Tricyclic; Intramolecular Heck coupling; Palladium bromide

Funding

  1. SJTU-Roche Joint Graduate Education Program

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A new and efficient synthesis of tricyclic 4-pyridone analogs through the intramolecular Heck coupling cyclization was described. This reaction features mild conditions and good functional group tolerance allowing for the preparation of several novel tricyclic 4-pyridone analogs. (C) 2014 Elsevier Ltd. All rights reserved.

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