4.4 Article

One pot direct synthesis of β-ketoesters via carbonylation of aryl halides using cobalt carbonyl

Journal

TETRAHEDRON LETTERS
Volume 55, Issue 25, Pages 3525-3528

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.04.087

Keywords

Aryl halides; Carbonylation; beta-Ketoesters; Imidazole Co-2(CO)(8)

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A direct method for the synthesis of beta-ketoesters from aryl halides (iodide, bromide) has been described by using cobalt carbonyl as carbon monoxide source in microwave irradiation. Using this protocol, a wide variety of substituted aryl halides has been successfully converted to corresponding beta-ketoesters. (C) 2014 Elsevier Ltd. All rights reserved.

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