Journal
TETRAHEDRON LETTERS
Volume 55, Issue 49, Pages 6694-6697Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.10.050
Keywords
Epoxide; Ring-opening; Graphite oxide; Metal-free conditions
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A simple, efficient, and general procedure for the ring-opening of epoxides with various alcohols to give the corresponding beta-alkoxy alcohols using graphite oxide (GO) as the catalyst, under very mild reaction conditions is described. The method proceeds in good to excellent yields and in short reaction times at room temperature under metal-free conditions. (C) 2014 Elsevier Ltd. All rights reserved.
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