4.4 Article

A one-pot three-component reaction in aqueous micellar medium: an easy route to chromeno[2,3-b]quinolinedione

Journal

TETRAHEDRON LETTERS
Volume 55, Issue 18, Pages 2924-2928

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.03.072

Keywords

Green chemistry; Multicomponent reaction; Hydrophobic effect; Chromone; Chromone-3-carbaldehyde; 1-Benzopyran

Funding

  1. CSIR, New Delhi, India [02(0029)/11/EMR-II]
  2. CSIR

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An efficient and green synthesis of hitherto unreported 5-aryl-3,3-dimethyl-2,3-dihydro-5aH-chromeno[2,3-b]quinoline-1,11(4H,5H)dione has been accomplished by a three-component reaction involving chromone-3-carbaldehyde, an aromatic amine, and 5,5-dimethyl-1,3-cyclohexanedione (dimedone) in 1.8 M aqueous TBAB solution. It is noteworthy that the TBAB/H2O system can be recovered and reused for seven cycles directly. (C) 2014 Elsevier Ltd. All rights reserved.

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