4.4 Article

Oxidative cleavage of α-sulfonyl ketones to carboxylic acids with Ce(NH4)2(NO3)6

Journal

TETRAHEDRON LETTERS
Volume 55, Issue 40, Pages 5548-5550

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.08.038

Keywords

alpha-Sulfonyl ketones; Oxidative cleavage; Ce(NH4)(2)(NO3)(6)

Funding

  1. Ministry of Science and Technology of the Republic of China [NSC 102-2113-M-037-005-MY2]

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Tandem oxidative cleavage of alpha-sulfonyl arylketones 2 with the combination of Ce(NH4)(2)(NO3)(6) and O-2 in MeCN afforded carboxylic acids 3 in moderate to good yields. The plausible reaction mechanism has been discussed. (C) 2014 Elsevier Ltd. All rights reserved.

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