4.4 Article

Selective fluorescence and naked eye detection of histidine in aqueous medium via hydrogen bonding assisted Schiff base condensation

Journal

TETRAHEDRON LETTERS
Volume 55, Issue 1, Pages 174-176

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.10.144

Keywords

Visible light excitation; Naked eye; Histidine; Cell imaging; DFT

Funding

  1. CSIR, New Delhi

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Visible light excitable rhodamine B derivative (TARDHD) has been developed for fluorescence and naked eye detection of histidine in aqueous medium. TARDHD shows 45 fold fluorescence enhancement in the presence of histidine. It forms Schiff base with histidine and stabilizes via intra-molecular H-bonding. TARDHD can efficiently detect intracellular histidine. (C) 2013 Elsevier Ltd. All rights reserved.

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