Journal
TETRAHEDRON LETTERS
Volume 54, Issue 38, Pages 5250-5252Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.07.090
Keywords
Copper-catalyzed; Cyanation; Aryl iodide; Nitriles
Categories
Funding
- National Natural Science Foundation of China [21272178]
- Natural Science Foundation of Zhejiang Province [LY12B02010]
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A simple copper-catalyzed cyanation of aryl iodide with the combination of urea and dimethyl sulfoxide as a cyanide source is achieved, providing nitriles in moderate to good yields. This new approach represents an exceedingly practical and safe method for the synthesis of aryl nitriles. (C) 2013 Elsevier Ltd. All rights reserved.
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