Journal
TETRAHEDRON LETTERS
Volume 54, Issue 45, Pages 6049-6052Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.08.096
Keywords
N-(ortho-Chloromethyl)aryl amide; Iodonium ylide; Indoline; Transition-metal free
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Funding
- Natural Science Foundation of China [21072054]
- New Teachers' Fund for Doctor Stations, Ministry of Education of China [20094306120003]
- Training Program Foundation for the Young Talents by Hunan Normal University of China [ET21003]
- Hunan Provincial Natural Science Foundation of China [12JJ2009]
- Scientific Research Fund of Hunan Provincial Education Department [12A095]
- Aid Program for Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province
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A transition-metal-free method for the synthesis of indolines has been developed. In the presence of K2CO3, the cyclization reaction of N-(ortho-chloromethyl)aryl amides and iodonium ylides proceeded smoothly at room temperature in moderate to good yields. (c) 2013 Elsevier Ltd. All rights reserved.
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