Journal
TETRAHEDRON LETTERS
Volume 54, Issue 21, Pages 2669-2673Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.03.043
Keywords
Aza-Michael reaction; Aqueous sodium carbonate solution; beta-Amino carbonyl compounds; Mono-alkylation
Categories
Funding
- National Natural Science Foundation of China [NSFC-20872183, 20972126, 21272185]
- Program for New Century Excellent Talents in University of the Ministry of Education China [NCET-10-0937]
- Education Department of Shaanxi Provincial Government [09JK776]
Ask authors/readers for more resources
A general and efficient aza-Michael reaction promoted by aqueous sodium carbonate solution has been developed. The reaction has complete mono-alkylation selectivity and proceeds with complete chirality retention for chiral amino esters. With a broad substrate scope, a well-common catalyst and simple operation, the catalytic approach provides a facile, practicable, economical, and environmentally benign method for the synthesis of beta-amino carbonyl compounds. (c) 2013 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
