Journal
TETRAHEDRON LETTERS
Volume 54, Issue 40, Pages 5505-5509Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.07.147
Keywords
Surfactant catalyzed reaction; Dehydration reaction in water; Dodecylbenzenesulfonic acid (DBSA); Chemoselective; 2-Substituted benzimidazoles
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Funding
- DST (India) [SR/FT/CS-023/2010, SR/FT/CS-092/2009]
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An efficient synthetic method has been developed for the facile synthesis of 2-substituted benzimidazoles in organized aqueous media in the presence of a surfactant (viz. DBSA) as catalyst and I-2 as co-catalyst. The method described has the advantages of operational simplicity, excellent yields, high chemoselectivity, and clean and green reaction profile. (C) 2013 Elsevier Ltd. All rights reserved.
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