Journal
TETRAHEDRON LETTERS
Volume 54, Issue 34, Pages 4561-4563Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.06.084
Keywords
Lecanindole; Indole sesquiterpene; Progesterone receptor agonist; Alkaloid
Categories
Funding
- Ministry of Education, Culture, Sports, Science and Technology of Japan [23780112]
- Grants-in-Aid for Scientific Research [23780112] Funding Source: KAKEN
Ask authors/readers for more resources
The first synthesis of the racemate of lecanindole D, an indole sesquiterpenoid with potent and selective agonist activity toward the progesterone receptor, has been achieved from a known tetracyclic alcohol by using a diastereoselective installation of its tertiary hydroxy group via an epoxide intermediate and a Pd(II)-mediated construction of the indole ring moiety as the key transformations. (C) 2013 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
