Journal
TETRAHEDRON LETTERS
Volume 54, Issue 38, Pages 5239-5242Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.07.081
Keywords
Indole enamide; cis-Enamide; Hydroamidation; Total synthesis
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Funding
- University of Auckland
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The synthesis of indolic cis-enamides using a ruthenium-mediated hydroamidation of indole alkynes with primary oxalamides or alpha-keto amides is reported. Using this method the total synthesis of igzamide and Z-coscinamides A and B has been achieved. (C) 2013 Elsevier Ltd. All rights reserved.
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