Journal
TETRAHEDRON LETTERS
Volume 54, Issue 16, Pages 2060-2062Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.02.008
Keywords
Fluorous-Fmoc reagent; Fluorous mixture synthesis; Fluorous solid phase extraction; Fluorous HPLC
Categories
Funding
- Ministry of Education, Science, Sports and Culture [23580154]
- Meiji Seika Pharma Co., Ltd
- Grants-in-Aid for Scientific Research [23790031, 23580154] Funding Source: KAKEN
Ask authors/readers for more resources
The concise synthesis of fluorous Fmoc (f-Fmoc) reagents bearing C3F7 or C4F9 or C6F13 chains were achieved by fluorous mixture synthesis. The fluorous tagging process was effectively conducted using Heck type reaction of the bis-diazonium salt and the corresponding fluorous olefine, each bearing a different fluorous tag, by a one-pot double tagging strategy. At the final stage, each f-Fmoc reagent was separated from the mixture of three f-Fmoc reagents by fluorous solid phase extraction. (c) 2013 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available