4.4 Article

A modified approach to the skeleton of trigonoliimines A and B

Journal

TETRAHEDRON LETTERS
Volume 54, Issue 4, Pages 300-302

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.11.033

Keywords

Indole alkaloids; Trigonoliimines A and B; Synthesis

Funding

  1. NSFC [21102026]
  2. State Key Laboratory of Drug Research [SIMM1106KF-03]

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Compound 4 which represents the skeleton of trigonoliimines A and B was readily obtained in six steps from N-phthaloyl tryptamine, the synthetic strategy employed here was versatile and flexible which also led to a novel bistryptamine framework. (C) 2012 Elsevier Ltd. All rights reserved.

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