Journal
TETRAHEDRON LETTERS
Volume 53, Issue 22, Pages 2715-2718Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.03.079
Keywords
Suzuki reaction; Chalcone; Coumarin; Microwaves; Green technology
Categories
Funding
- FAPESP
- CNPq
- CAPES
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Chalcones and coumarins are important naturally occurring plant constituents and display a wide range of pharmacological and biological activities. In an environmentally benign approach, synthesis of biphenyl chalcone and coumarin derivatives was successfully accomplished via Suzuki coupling by using PEG-400 as a solvent under microwave irradiation. Salient feature of this methodology includes: short reaction time, good to excellent yields, and prominent tolerance of different functional groups. (C) 2012 Elsevier Ltd. All rights reserved.
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