Journal
TETRAHEDRON LETTERS
Volume 53, Issue 24, Pages 3056-3060Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.04.022
Keywords
Hantzsch; Pyrrole; Three-component; Heterocycle
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Pyrroles containing a 2,3-dicarbonyl substitution pattern are synthesized in one step via a three-component Hantzsch procedure. The normally difficult-to-access substrates are readily obtained in short reaction times and in moderate to good yields, giving pharmaceutically attractive products containing multiple handles for further elaboration. (C) 2012 Elsevier Ltd. All rights reserved.
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