4.4 Article

CuI-catalyzed one-pot synthesis of benzothiazolones from 2-iodoanilines-derived carbamates and sodium sulfide

Journal

TETRAHEDRON LETTERS
Volume 53, Issue 20, Pages 2511-2513

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.03.006

Keywords

Coupling

Funding

  1. Ministry of Science and Technology [2009ZX09501-00]
  2. Chinese Academy of Sciences
  3. National Natural Science Foundation of China [20632050, 20921091]

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A copper-catalyzed procedure was developed for assembling benzothiazolones from ethyl 2-iodophenylcarbamates and sodium sulfide. A number of functional groups, such as methoxy, acyl, amide, carboxylate, trifluoromethyl, fluoro, and chloro, were tolerated under these conditions, providing benzothiazolones in good yields. (C) 2012 Elsevier Ltd. All rights reserved.

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