Journal
TETRAHEDRON LETTERS
Volume 53, Issue 31, Pages 3981-3983Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.05.081
Keywords
Coupling
Categories
Funding
- Ministry of Science and Technology [2009ZX09501-00]
- Chinese Academy of Sciences
- National Natural Science Foundation of China [20632050, 20921091]
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CuI/N,N-dimethylglycine catalyzed coupling of aryl bromides with substituted oxazolidinones took place at 120 degrees C in DMF, affording the corresponding N-arylation products with good to excellent yields. A number of functional groups, such as ketone, nitrile, nitro, methoxy, and hydroxyl were tolerated under these conditions, thereby allowing diversity synthesis of N-aryloxazolidinones. (C) 2012 Elsevier Ltd. All rights reserved.
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