4.4 Article

Total synthesis of (±)-monomorine

Journal

TETRAHEDRON LETTERS
Volume 53, Issue 42, Pages 5660-5662

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.08.041

Keywords

Hydrogenation; Claisen-Schmidt; Monomorine

Funding

  1. Pfizer

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An efficient, two-operation synthesis of the trail ant pheromone (+/-)-monomorine is reported. The synthesis features an aqueous Claisen-Schmidt condensation followed by the stereocontrolled installation of the three resident stereocenters in a single operation. (C) 2012 Elsevier Ltd. All rights reserved.

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