Journal
TETRAHEDRON LETTERS
Volume 53, Issue 13, Pages 1546-1549Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.12.104
Keywords
Stetter reaction; Aldehydes; alpha,beta-Unsaturated ketones; 1,4-Diketones
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Funding
- UGC
- CSIR, New Delhi
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An improved method has been developed for the hydroacylation of enones with aldehydes employing bis-5-(2-hydroxyethyl)-1,3-thiazolium bromide/Et3N system to afford the corresponding 1,4-diketones in good yields. This method is effective for the preparation of 1,4-diketones from both aromatic and aliphatic aldehydes. (C) 2011 Elsevier Ltd. All rights reserved.
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