4.4 Article

Facile syntheses of 2-substituted 3-cyanochromones

Journal

TETRAHEDRON LETTERS
Volume 53, Issue 28, Pages 3630-3632

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.05.031

Keywords

2-Substituted 3-cyanochromones; 3-(2-Hydroxyphenyl)-3-oxopropionitrile; 3-Hetaryl-2-(2-hydroxybenzoyl) acrylonitriles; Acylation

Funding

  1. OJSC CSRIT Technomash

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A simple and general route to 3-cyanochromones containing various substituents on position 2 of the ring is developed. The method is based on condensation of 3-(2-hydroxyphenyl)-3-oxopropionitrile with acid chlorides or anhydrides in pyridine at room temperature. (C) 2012 Elsevier Ltd. All rights reserved.

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