Journal
TETRAHEDRON LETTERS
Volume 53, Issue 28, Pages 3627-3629Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.05.010
Keywords
Diaminothiazole; Synthesis; One-pot; Sequential multicomponent; Nitroguanidine
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Funding
- University Grants Commission, Govt. of India
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A facile one-pot sequential three-component route to 2,4-diaminothiazoles is reported. The new approach employs the mildest reaction conditions and commercially available reagents to generate diverse 2-alkyl/arylamino-4-amino-5-aroyl/heteroylthiazoles in short reaction times, good yield, and purity. (C) 2012 Elsevier Ltd. All rights reserved.
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