4.4 Article

Graphite oxide mediated oxidative aromatization of 1,4-dihydropyridines into pyridine derivatives

Journal

TETRAHEDRON LETTERS
Volume 53, Issue 19, Pages 2473-2475

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.03.026

Keywords

Graphite oxide; 1,4-Dihydropyridine derivatives; Oxidative aromatization; Pyridine derivatives

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A new approach utilizing graphite oxide as an oxidizing agent is applied for the oxidative aromatization of 1,4-dihydropyridines. Graphite oxide efficiently aromatized Hantzsch 1,4-dihydropyridines into their corresponding pyridine derivatives in excellent yields. The reaction was carried out in toluene at 100 degrees C. (C) 2012 Elsevier Ltd. All rights reserved.

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