4.4 Article

An efficient and simple method for synthesis of 2,2-disubstituted-2H-chromenes by condensation of a phenol with a 1,1-disubstituted propargyl alcohol using BF3•Et2O as the catalyst

Journal

TETRAHEDRON LETTERS
Volume 53, Issue 39, Pages 5275-5279

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.07.077

Keywords

2,2-Disubstituted-2H-chromenes; Phenol; Cyclocondensation; 1,1-Disubstituted propargyl alcohol; BF3 center dot Et2O; Lewis acid catalysis

Funding

  1. C.S.I.R., New Delhi
  2. U.G.C., New Delhi

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An efficient and simple method for the synthesis of 2,2-disubstituted-2H-chromenes by one-step cyclocondensation of a phenol with a variety of 1,1-disubstituted propargyl alcohols using BF3 center dot Et2O as the catalyst is described. (c) 2012 Elsevier Ltd. All rights reserved.

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