Journal
TETRAHEDRON LETTERS
Volume 52, Issue 1, Pages 80-84Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.10.150
Keywords
Dihydropyrimidinone; Green chemistry; Biginelli reaction; Microwave reaction; Multi-component reaction
Categories
Funding
- Nanyang Technological University [RG50/08]
- Ministry of Health, Singapore [NMRC/H1N1R/001/2009]
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The synthesis of dihydropyrimidinones via a clean multi-component Biginelli reaction under microwave irradiation is reported. The copper-catalyzed process proved to be simple, efficient, economical, and environmentally friendly. (C) 2010 Elsevier Ltd. All rights reserved.
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