4.4 Article

Synthesis of (-)-hygrine, (-)-norhygrine, (-)-pseudohygroline and (-)-hygroline via Nef reaction

Journal

TETRAHEDRON LETTERS
Volume 52, Issue 49, Pages 6566-6568

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.09.118

Keywords

Nef reaction; Henry reaction; Diastereoselective; Tropane alkaloid; Sedum alkaloid

Funding

  1. DST
  2. CSIR, New Delhi

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Synthesis of tropane alkaloids (-)-hygrine, (-)-norhygrine and sedum alkaloids (-)-pseudohygroline and (-)-hygroline is described from L-proline via Henry and Nef reactions. (C) 2011 Elsevier Ltd. All rights reserved.

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