Journal
TETRAHEDRON LETTERS
Volume 52, Issue 11, Pages 1157-1160Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.12.101
Keywords
Quinine; Organocatalyst; Phospho-Aldol reaction; Diphenyl phosphite; N-alkylated isatins
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Funding
- National Natural Science Foundation of China [20802075, 21042006]
- Chinese Academy of Sciences
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Cinchona alkaloids were first successfully reported to promote enantioselective Phospho-Aldol reaction of diphenyl phosphite to a variety of N-alkylated isatin derivatives in good to excellent yields (up to 99%) and moderate to good enantioselectivities (up to 73% ee) almost in no time. (C) 2011 Elsevier Ltd. All rights reserved.
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