4.4 Article

Trigonoines A and B, two novel alkaloids from the leaves of Trigonostemon lii

Journal

TETRAHEDRON LETTERS
Volume 52, Issue 25, Pages 3186-3188

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.03.015

Keywords

Trigonoine A; Trigonoine B; beta-Carboline alkaloid; Trigonostemon lii

Funding

  1. Ministry of Science and Technology of China [2009CB940900, 2009CB522300]
  2. National Natural Science Fund of China [21072199, 30830114]
  3. Natural Science Fund of Yunnan Province [2009CD112]
  4. Foundation of Chinese Academy of Sciences
  5. Yong Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI047]

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Two novel alkaloids, trigonoine A containing a 2,8-diazabicyclo[3.3.1]nonane ring system and trigonoine B formed by a combination of a 2,3-dihydroquinolin-4-one and 3H-pyrrolo[2,3-c]quinoline rearranged from B-carboline skeleton were isolated from the leaves of Trigonostemon lii. Their structures were elucidated by 10 and 20 NMR spectroscopic methods. (C) 2011 Elsevier Ltd. All rights reserved.

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