Journal
TETRAHEDRON LETTERS
Volume 52, Issue 15, Pages 1804-1806Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.02.027
Keywords
Synoxazolidinone; 4-Oxazolidinone; Synoicum pulmonaria; Antibacterial; Anticancer
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Synoxazolidinone C is a new member of the synoxazolidinone family of compounds which are dibrominated guanidinium 4-oxazolidinones isolated from the sub-Arctic ascidian Synoicum pulmonaria. The compound was isolated along with synoxazolidinones A and B from the same ascidian extract. Spectroscopic methods revealed that the synoxazolidinone C differed from the other synoxazolidinones by an unprecedented bicyclic partial structure, containing an additional pyrrolidine ring. Synoxazolidinone C exhibited both antibacterial and anticancer activities. (C) 2011 Elsevier Ltd. All rights reserved.
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