Journal
TETRAHEDRON LETTERS
Volume 52, Issue 10, Pages 1060-1061Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.12.089
Keywords
Polyunsaturated amino ketone; Marine natural product; Eicosapentaenoic acid; Grignard reaction
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Funding
- Norwegian Research Council (KOSK II)
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The first synthesis of (all-Z)-1-[(2-phenylethyl)amino]-octadeca-6,9,12,15-tetraen-3-one has been achieved in nine steps and in 13% overall yield using eicosapentaenoic acid as the starting material. (C) 2010 Elsevier Ltd. All rights reserved.
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