Journal
TETRAHEDRON LETTERS
Volume 52, Issue 29, Pages 3765-3768Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.05.059
Keywords
Marine sponges; Terpenoids; Puupehenone; Antioxidants
Categories
Funding
- FEBRAS [09-III-C-05-145]
- Presidium of the Russian Academy of Sciences
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A new unsymmetrical puupehenone-related dimer, diplopuupehenone, comprising puupehenone and puupehenol segments, was isolated from the marine sponge Dysidea sp., along with the known metabolites, puupehenone and bispuupehenone. The structure of diplopuupehenone was established from spectroscopic data and by spectroscopic analysis of an acetoxy derivative. Diplopuupehenone showed 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity with an IC50 value of 8 mu M. (C) 2011 Elsevier Ltd. All rights reserved.
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