4.4 Article

Ferric sulfate [Fe2(SO4)3•xH2O]: an efficient heterogeneous catalyst for the synthesis of tetrahydroquinoline derivatives using Povarov reaction

Journal

TETRAHEDRON LETTERS
Volume 52, Issue 35, Pages 4539-4542

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.06.080

Keywords

Ferric sulfate [Fe-2(SO4)(3)center dot xH(2)O]; Heterogeneous catalyst; Tetrahydroquinoline derivatives; Povarov reaction; Multicomponent reactions

Funding

  1. IIT Guwahati
  2. UGC

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Fe-2(SO4)(3)center dot xH(2)O can be used as an efficient and reusable catalyst for the synthesis of pyrano- and furanotetrahydroquinolines via one-pot three-component Povarov reaction involving aromatic aldehydes, aromatic amines, and cyclic enol ethers. The catalyst is recyclable, economically viable, and environmentally benign. This protocol provides good yields and diastereoselectivity as well as applicability on a wide range of substrates. (C) 2011 Elsevier Ltd. All rights reserved.

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