Journal
TETRAHEDRON LETTERS
Volume 52, Issue 11, Pages 1225-1227Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.01.048
Keywords
3-Arylcoumarins; Suzuki reaction; 3-Chlorocoumarin; N,N '-Bis(salicylidene)-ethylenediamino-palladium catalyst
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Funding
- Spanish Ministry [PS0900501]
- Xunta da Galicia [INCITE09E2R20303 5ES, PGIDIT09CSA030203PR]
- Fundacao de Ciencia e Tecnologia [SFRH/BD/61262/2009]
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A convenient, new, and effective protocol for a rapid synthesis of different substituted 3-arylcoumarins is reported. The developed synthetic route involves Pd-catalyzed cross-coupling reaction, using a catalytic complex Pd-salen. Under these conditions, a series of different substituted boronic acids have been successfully reacted with a coumarin halide to afford the coupling products in good yields. (C) 2011 Elsevier Ltd. All rights reserved.
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