Journal
TETRAHEDRON LETTERS
Volume 52, Issue 9, Pages 980-982Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.12.053
Keywords
4,5-Disubstituted 1,2,3-(NH)-triazoles; One-pot; Carbonylative; 1,3-Dipolar cycloaddition; Atom economic
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Funding
- Scientific Research Foundation for the State Education Ministry [107108]
- National Science Foundation of PR China [J0730425]
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A one-pot method for the synthesis of 4,5-disubstituted-1,2,3-(NH)-triazoles via carbonylative Sonogashira reaction/1,3-dipolar cycloaddition of terminal acetylenes, carbon monoxide, aryl iodides, and sodium azide was developed. A series of new 4,5-disubstituted-1,2,3-(NH)-triazoles were prepared readily under mild conditions. (C) 2010 Elsevier Ltd. All rights reserved.
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