4.4 Article

Facile synthesis of 3,4-diiododihydrothiophenes via electrophilic iodocyclization

Journal

TETRAHEDRON LETTERS
Volume 52, Issue 8, Pages 936-938

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.12.075

Keywords

3,4-Diiododihydrothiophenes; Iodocyclization; Iodine; S-4-Hydroxy-2-butynyl ethanethioates

Funding

  1. Japan Society for Promotion of Science (JSPS)
  2. China Scholarship Council (CSC)

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A facile, efficient, and general synthetic method for the construction of 3,4-diiododihydrothiophenes has been developed via the electrophilic iodocyclization of various S-hydroxy-2-butynyl ethanethioates. Application of the resulting iodine-containing products in organic transformations has been investigated. (C) 2010 Elsevier Ltd. All rights reserved.

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