4.4 Article

Total synthesis of (+)-aspergillide C

Journal

TETRAHEDRON LETTERS
Volume 52, Issue 12, Pages 1372-1374

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.01.078

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Funding

  1. Basic and Applied Research for Innovations in the Bio-oriented Industry (BRAIN)
  2. Grants-in-Aid for Scientific Research [23390026] Funding Source: KAKEN

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The enantioselective total synthesis of aspergillide C. a member of a novel class of 14-membered macro-lides isolated from the marine-derived fungus Aspergillus ostionus strain 01F313, has been accomplished employing a highly diastereoselective intramolecular oxy-Michael reaction as the key step. (C) 2011 Elsevier Ltd. All rights reserved.

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