4.4 Article

Base and concentration effects on the product distribution in copper-promoted alkyne-azide cycloaddition: additive-free route to 5-iodo-triazoles

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 3, Pages 550-553

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.11.089

Keywords

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Funding

  1. American Chemical Society Petroleum Research Fund [47965-G7]
  2. TCU
  3. ACS Division of Medicinal Chemistry

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Formation of 5-iodo-triazoles in Cul-promoted cycloadditions between alkynes and azides is controlled by DMAP and low alkyne concentrations. (C) 2009 Elsevier Ltd. All rights reserved.

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