4.4 Article

Copper(0) in the Ullmann heterocycle-aryl ether synthesis of 4-phenoxypyridine using multimode microwave heating

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 2, Pages 248-251

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.10.126

Keywords

Ullmann synthesis; Copper nanoparticles; Microreactors; Microwave heating; Catalysis

Funding

  1. European Commission [NMP3-CT-2005-515703]
  2. Royal Society [2008/R4]
  3. DSM Research, Friesland-Campina
  4. Technology Foundation STW [GSPT-07974]

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The action of nanoparticulate copper catalysts with a mean particle size of 10 nm in the Ullmann ether synthesis is reported using multimode microwave heating and employing stable chloropyridine salts and unactivated phenol, with stabilized copper nanoparticles outperforming other copper catalysts in terms of stability and reusability. (C) 2009 Elsevier Ltd. All rights reserved.

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