4.4 Article

Chiral carbene approach to gold-catalyzed asymmetric cyclization of 1,6-enynes

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 2, Pages 404-406

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.11.039

Keywords

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Funding

  1. Ministry of Education, Culture, Sports, Science, and Technology, Japan
  2. Egyptian Government
  3. Grants-in-Aid for Scientific Research [21790013, 20249002] Funding Source: KAKEN

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Chiral C-2-symmetric N-heterocyclic carbenes (NHCs) were tested for their stereocontrolling abilities in gold(I)-catalyzed asymmetric cyclization of 1,6-enynes giving the corresponding cyclopentane derivatives with moderate enantioselectivity of up to 59%. (C) 2009 Elsevier Ltd. All rights reserved.

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