4.4 Article

Organocatalytic diastereoselective dibromination of alkenes

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 20, Pages 2708-2712

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.03.043

Keywords

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Funding

  1. Swedish National Research Council
  2. Swedish Governmental Agency for Innovation Systems (VINNOVA)
  3. VR
  4. VINNOVA

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A highly diastereoselective pyrrolidine-promoted dibromination of alkenes by combination of NBS and succinimide is presented. The pyrrolidine-mediated dibromination of alkenes is higly anti-selective and gives the corresponding products in moderate to high yields and up to >25:1 dr. (C) 2010 Elsevier Ltd. All rights reserved.

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